|Title||Hydrogels for brain repair after stroke: an emerging treatment option.|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||LR Nih, ST Carmichael, and T Segura|
|Journal||Current Opinion in Biotechnology|
|Pagination||155 - 163|
Stroke disability is the only major disease without an effective treatment. The substantial clinical burden of stroke in disabled survivors and the lack of a medical therapy that promotes recovery provide an opportunity to explore the use of biomaterials to promote brain repair after stroke. Hydrogels can be injected as a liquid and solidify in situ to form a gelatinous solid with similar mechanical properties to the brain. These biomaterials have been recently explored to generate pro-repair environments within the damaged organ. This review highlights the clinical problem of stroke treatment and discusses recent advances in using in situ forming hydrogels for brain repair.
|Short Title||Current Opinion in Biotechnology|